Cholesterol is not evil—it is vital to human life. Approximately 80% of cholesterol is
manufactured in the body. 50% of cell walls are made up of cholesterol. Almost all cells make cholesterol with the majority synthesized in the liver. Cholesterol is the precursor to many critical compounds and hormones including male and female hormones, Vitamin D and bile acids. Healthy people maintain a relatively constant blood cholesterol level no matter how much cholesterol they eat
If we consume too much cholesterol through dietary sources, the liver makes less cholesterol to even it out. The synthesis of cholesterol is controlled mostly by insulin. The pancreas produces insulin as a response to ingested sugars and starches to control blood sugar levels. High levels of insulin resulting from high intakes of sugars and starches stimulate the production of cholesterol and disrupt normal control (or balancing) mechanisms of the body
In other words, cholesterol is necessary. Low-density lipoprotein (LDL) carries cholesterol to the tissues for all types of biologic processes most of which are healthy. Under normal circumstances, cholesterol passes in and out of the blood vessel wall without difficulty. You’ll hear LDL deemed the “bad cholesterol” from the medical profession, on TV commercials, doctors on radio talk shows, and in health articles but it isn’t bad at all. It is vital, not evil.
LDL is simply a carrier of cholesterol from the liver where it is synthesized, manufactured and distributed to the tissues to be used. However, in the presence of high blood sugar or from oxidative stress, the LDL experiences chemical changes the body perceives as dangerous and reacts.
How does your body respond? The “Velcro Effect” begins when certain chemicals are released by the warriors that fight off danger. Your body senses danger from the LDL chemical changes and the Velcro pops out attaching to the circulating monocytes. Your body has declared war……..
The important point to remember is—there wasn’t an invader, germ or infection—just LDL experiencing chemical changes from sugar, starches or oxidation and the warriors responded. Under normal circumstances, the LDL would never get into the artery wall and cause a plaque unless the HDL changed from oxidation or high blood sugar in the presence of inflammation
• High cholesterol is a reflection of a high carbohydrate diet.
• High carbohydrate-low fat diets cause inflammation and oxidation that cause the aggressive macrophages to eat the LDL and deposit it into the artery wall.
• LDL is normal and harmless without inflammation.
• Without inflammation, the cholesterol level in the blood is largely irrelevant.
The current statin research proves:
• Statins
do modestly lower blood cholesterol levels.
• Statins
do modestly lower heart attacks rates in middle-aged men with known coronary heart disease.
• Statins
do not reduce mortality or heart attack rates in women.
• Statins
do not lower mortality rates in men who have not been diagnosed with heart disease.
There is research that shows very promising benefits of statin medications; however, the benefits of statins may not be what you think. The benefits start long before there is a reduction in cholesterol levels.
Statins have beneficial effects that are independent of lowering your cholesterol. Statins can improve endothelial function, have anti-clotting effects, positive antioxidant benefits and may reduce the risk of plaque rupture. Most importantly, they’ve been shown to have anti-inflammatory benefits.
Statins seems to inhibit the artery wall from creating the “Velcro Effect” in inflammation written about earlier. They’ve also been shown to reduce C-reactive protein levels, which are a key marker to inflammation. So, they have benefits but I wonder how long it will take before they are marketed differently to reveal the true benefits.
Even though statins show many benefits; there are other ways of achieving the same health benefits. And, importantly, those other options are definitely friendlier on your metabolism
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